Biology

Human physiology basics

Homeostasis, circulation, nerves, immunity.

Basics

Homeostasis

Keeping the internal environment in a narrow range. Negative feedback is the default (temperature, blood glucose). Positive feedback is rare and amplifying (oxytocin in birth). Hormones are slow and broad; nerves are fast and local.

Circulation

Heart: right side → lungs → left side → body. Arteries are high pressure, capillaries exchange, veins return. Hemoglobin in red cells carries O₂. ABO and Rh set transfusion compatibility.

Nerves

Resting potential is mostly K⁺ leak. An action potential: Na⁺ in (depolarize), then K⁺ out (repolarize). Neurotransmitters at synapses. Central (brain, spinal cord) versus peripheral.

Immunity

Innate: barriers, phagocytes, inflammation. Adaptive: B-cell antibodies, T cells. Memory cells make a second exposure faster. Vaccines create memory without the full disease.

Formulas

Cardiac output

CO = HR × SV

Blood one ventricle pumps per minute. Exercise raises both HR and SV.

Symbols

  • HR heart rate
  • SV stroke volume

Equilibrium potential (K⁺, ~37 °C)

E_K ≈ 61 mV · log₁₀ ([K⁺]_o / [K⁺]_i)

Membrane voltage if only that ion permeated. Rest is a weighted mix.

Symbols

  • [K⁺]_o outside concentration
  • [K⁺]_i inside concentration

Key table

Blood types A/B antigens; O has neither, AB both. Rh+ has D antigen
Core temperature about 37 °C

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